CasNo: 70-18-8
Molecular Formula: C10H17N3O6S
Appearance: White cryst. powder
Quality products make an important contribution to long-term revenue and profitability. Manufacturer supply Glutathione 70-18-8 with sufficient stock and high standard
ChEBI: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Glutathione (GSH) is a tripeptide (γ-glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status. The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.
The CAS number of Glutathione is 70-18-8.
Synonyms for Glutathione 70-18-8:Glutathione(8CI);Glycine, N-(N-L-g-glutamyl-L-cysteinyl)-;Copren;Glutathion;Glutathione-SH;Glutide;Glutinal;Isethion;L-Glutathione;N-(N-L-g-Glutamyl-L-cysteinyl)glycine;Tathione;g-Glutamylcysteinylglycine;g-L-Glutamyl-L-cysteinylglycine;Glycine, L-g-glutamyl-L-cysteinyl-;GSH;L-Glutathione Reduced;
L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.
InChI:InChI=1/C10H17N3O6S/c11-5(1-2-7(14)15)9(18)13-6(4-20)10(19)12-3-8(16)17/h5-6,20H,1-4,11H2,(H,12,19)(H,13,18)(H,14,15)(H,16,17)
Relevant articles related to Glutathione:
Article |
Source |
Rate constant determination for the reaction of hydroxyl and glutathione thiyl radicals with glutathione in aqueous solution |
Mezyk, Stephen P. , p. 8861 - 8866 (1996) |
Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives |
Bienvenu, Céline,Greiner, Jacques,Vierling, Pierre,Giorgio, Christophe Di , p. 3309 - 3311 (2010) |
Dissecting the catalytic mechanism of trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling |
Leroux, Alejandro E.,Haanstra, Jurgen R.,Bakker, Barbara M.,Krauth-Siegel, R. Luise , p. 23751 - 23764 (2013) |
Jilin Tianyun New Materials Co., Ltd is a quality supplier of Glutathione. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Glutathione 70-18-8.