• 4-Aminobenzoic acid

4-Aminobenzoic acid

  • CasNo：150-13-0
  • Purity：99%

Product Details;

CasNo： 150-13-0

Molecular Formula： C7H7NO2

Appearance： White to off white crystalline powder

Chinese factory supply 4-Aminobenzoic acid 150-13-0 in stock with high standard

  • Molecular Formula:C7H7NO2
  • Molecular Weight:137.138
  • Appearance/Colour:White to off white crystalline powder 
  • Vapor Pressure:3.45E-05mmHg at 25°C 
  • Melting Point:186-189 °C 
  • Refractive Index:1.5323 (estimate) 
  • Boiling Point:339.9 °C at 760 mmHg 
  • PKA:2.50, 4.87(at 25℃) 
  • Flash Point:159.4 °C 
  • PSA：63.32000 
  • Density:1.315 g/cm3 
  • LogP:1.54820 

4-Aminobenzoic acid(Cas 150-13-0) Usage

Chemical Description

 4-Aminobenzoic acid (PABA) is an organic compound featuring both an amino group and a carboxylic acid group, known for its role as a sunscreen agent and its involvement in cellular metabolism.
Uses 4-Aminobenzoic acid is utilized as a sunscreen agent to protect against UV radiation and has applications as a pharmaceutical and dye intermediate. It also exhibits antibacterial, antiviral, and antioxidant properties, making it beneficial in treating certain dermatological conditions and as an essential nutrient for some microorganisms.

Therapeutic Function

Sunscreen agent, Antirickettsial

Hazard

Questionable carcinogen.

Flammability and Explosibility

Nonflammable
Manufacturing Method It is synthesized by reducing p-nitrobenzoic acid in a hydrogen atmosphere using a catalyst (like Raney nickel) in a solution containing water and tetrahydrofuran, followed by purification processes including filtration and crystallization.

InChI:InChI=1/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)/p-1

150-13-0 Relevant articles

Synthesis and antimycobacterial activity of some coupling products from 4-aminobenzoic acid hydrazones

Ş.Güniz Küçükgüzel a , Sevim Rollas a , Ilkay Küçükgüzel a , Muammer Kiraz b

, European Journal of Medicinal Chemistry Volume 34, Issue 12 , December 1999, Pages 1093-1100

Antituberculosis and antibacterial effects have been shown with various 4-aminobenzoic acid substituted benzalhydrazones [1]. Furthermore, the coupling products starting from diazonium salts of 4-aminobenzoic acid hydrazide substituted benzalhydrazones with indole have also been reported to possess promising antibacterial and antitubercular activities [2]. These observations prompted us to synthesize some novel coupling products of 4-aminobenzoic acid hydrazide substituted benzalhydrazone derivatives.

Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid

J Parekh, P Inamdhar, R Nair, S Baluja

, Journal of the Serbian Chemical Society 2005 Volume 70, Issue 10, Pages: 1155-1162

The following Schiff bases have been synthesized: (1) 4-(2-chlorobenzylidene)amino benzoic acid JP1, (2) 4 (furan-2-ylmethylene)amino benzoic acid JP2, (3) 4-[(3-phenylallylidene)amino]benzoic acid JP3, (4) 4 (2-hydroxybenzylidene)amino benzoic acid JP4, (5) 4 (4-hydroxy-3-methoxybenzylidene)amino benzoic acid JP5 and (6) 4 (3-nitrobenzylidene)amino benzoic acid JP6.

Sulfonated covalent triazine polymer loaded with Pd nanoparticles as a bifunctional catalyst for one pot hydrogenation esterification reaction

Ravi, S.,Raza, A. Ahmed,Sheriff, A. K. Ibrahim,Tajudeen, S. Syed

, (2021)

Highly dispersed Pd nanoparticles over c...

Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

Coleman, Tom,Wong, Siew Hoon,Podgorski, Matthew N.,Bruning, John B.,De Voss, James J.,Bell, Stephen G.

, p. 5915 - 5927 (2018)

The cytochrome P450 enzymes execute a ra...

Ruthenium nanoparticles supported over mesoporous TiO2 as an efficient bifunctional nanocatalyst for esterification of biomass-derived levulinic acid and transfer-hydrogenation reactions

Mandi, Usha,Salam, Noor,Kundu, Sudipta K.,Bhaumik, Asim,Islam, Sk. Manirul

, p. 73440 - 73449 (2016)

We have supported ruthenium nanoparticle...

Kinetic and mechanistic investigations and thermodynamic quantities for different steps involved in the mechanism of oxidation of procainamide by hexacyanoferrate(III) in aqueous alkaline medium: a spectrophotometric study

Meti,Lamani,Naikar,Sutar,Nandibewoor,Chimatadar

, p. 1485 - 1493 (2015)

The kinetics of oxidation of procainamid...

150-13-0 Process route

4'-Carboxy-N-(4-dimethylamino-benzyliden)anilin
140140-19-8

4'-Carboxy-N-(4-dimethylamino-benzyliden)anilin

4-amino-benzoic acid
150-13-0,159246-81-8,8014-65-1

4-amino-benzoic acid

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

Conditions
Conditions Yield
With borate buffer; water; In methanol; at 25 ℃; Rate constant; Kinetics; Mechanism; ΔG(activ.), ΔH(activ.), ΔS(activ.);
 
Procaine
59-46-1,91484-72-9

Procaine

4-amino-benzoic acid
150-13-0,159246-81-8,8014-65-1

4-amino-benzoic acid

2-(Diethylamino)ethanol
100-37-8

2-(Diethylamino)ethanol

Conditions
Conditions Yield
With Tris-HCl buffer; human liver carboxylesterase pI 4.5; at 37 ℃; pH=7.4; Enzyme kinetics;
 
With sodium hydroxide; Kinetics;
 

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